Hemorrhagic fever with renal syndrome

ELISA

Hemorrhagic Fever with Renal Syndrome, or HFRS, is an acute viral disease caused by hantaviruses. It is a zoonotic infection, meaning that the virus is naturally maintained in animals and can occasionally be transmitted to humans.

The major clinical manifestations includes:

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Low blood pressure

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Thrombocytopenia

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Vascular leakage

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Acute kidney injury

Reservoir hosts for Hantavirus:

Hantaviruses are maintained in nature by rodents, which serve as their main reservoirs. Most hantaviruses are closely linked to particular rodent host species. Infected rodents usually show no signs of disease but can shed the virus in urine, feces, and saliva for extended periods. Humans may become infected after exposure to contaminated dust, surfaces, or materials. HFRS does not usually spread from person to person.

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5.pngHFRS primarily peaks during:

  • May–June
  • October–December
 6.pngPeople at higher risk include:

  • farmers, agricultural workers
  • hunters, hikers, campers
  • people living in endemic regions
  • field workers

Diagnostics

Early diagnosis can be challenging because the first symptoms may resemble influenza, COVID-19, leptospirosis, dengue, viral pneumonia, or sepsis

Laboratory confirmation may include:

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Kits for detection of hantavirus-specific IgM antibodies


Cat. №

Kit Name

Additional information

4904

VectoHanta-IgM

Detection of IgM to hantaviruses

4905

Hanta-IgM-express-BEST      

Detection of IgM to hantaviruses by immunochromatography

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Kits for detection of IgG antibodies with rising titres in paired samples


Cat. №

Kit Name

Additional information

4902

VectoHanta-IgG

Detection of IgG to hantaviruses

4903

Hanta-IgG-express-BEST      

Detection of IgG to hantaviruses by immunochromatography

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RT-PCR during the acute phase, when viral RNA may be present in blood

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