Single nucleotide polymorphisms and mutations in human genes
PCR
RealBest-Genetics kits are designed for various diagnostic areas
PCR analysis using RealBest-Genetics kits
Sample types
- Buccal swabs (in Transport solution, for example No8894)
- Whole blood
DNA extraction kits
Manual extraction:
8845 RealBest-Genetics DNA-express
Automated DNA extraction (KingFisher Flex, Auto-Pure 96, RbMag):
8846 RealBest GenMag
RealBest-Genetics Kits for mutations detection
Methods: asymmetric PCR with following melting curve analysis of PCR products or real-time PCR for allele detection
Multiplex PCR: detection up to three targets in one test tube – each target is detected by specific fluorescent channel; different alleles result in different melting temperatures
Easy-to-use: Lyophilized Ready Master Mix in 48/96-tube plates – just add a sample of extracted DNA into tubePCR cyclers: kits are compatible with plate-type real-time PCR cyclers CFX96 (Bio- Rad, USA), Gentier 96E/R (Xi’an TianLong, S&T Co., Ltd., China) and others with similar characteristics after validation
Analysis of results
GP.RealBest Diagnostics software for convenient workflow and interpretation of results